Multiomics in atherosclerotic cardiovascular disease

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Multiomics in atherosclerotic cardiovascular disease

Abstract

Atherosclerotic cardiovascular disease (ASCVD) is among the leading causes of death worldwide, and technological advances have made it possible to expand the repertoire of biomarkers used in diagnostics and treatment of ASCVD. These include different omics (genomics, epigenomics, transcriptomics, proteomics, and metabolomics). We introduce the various layers of omic data and how they can be used in diagnostics and treatment of ASCVD. Further, we discuss future possibilities of combining multiomic data with machine learning (ML) and artificial intelligence (AI) to develop algorithms for facilitating precision medicine.

https://www.atherosclerosis-journal.com/article/S0021-9150(25)01312-7/fulltext

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